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Side Effects

in this section: Side Effects | Tufts Study | Rhabdomyolysis | LDL and HDL Cholesterol | FDA Regulation


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Crestor Side Effects

Crestor is an effective treatment used to lower cholesterol, but it has been linked to dangerous side effects like rhabdomyolysis and kidney damage. You are twice as likely to develop these side effects using Crestor than with other statins.

If you or a loved one has suffered from one of these dangerous side effects, you need the help of the experienced Crestor side effect attorneys of Weitz & Luxenberg. For a FREE lawsuit case evaluation, fill out this simple form and your Crestor claim will be evaluated within 24 hours.

Rhabdomyolysis

Some doctors have been hesitant to prescribe rosuvastatin because of concerns that this agent might have a higher incidence of rhabdomyolysis (a severe undesired side effect) than other statins; this negative impact on sales performance has been much more pronounced in the United States than in other countries.

The FDA has indicated that "it does not appear that the risk [of rhabdomyolysis] is greater with Crestor than with other marketed statins", but has mandated that a warning about this side effect, as well as a kidney toxicity warning, be added to the product label.

Kidney Damage

Regarding kidney function effects, recent reviews of published trial data, focusing on renal function, on placebo vs. statin, and tracking renal function over time have shown a small but distinct effect of statins to lessen renal dysfunction, when added to treatment (compared to placebo), and to slow the progression of further renal function decline over time.

All the statins have a somewhat dose related response to increase urine protein levels, rosuvastatin the strongest association.

Because increased urine protein has long been relied upon as a warning sign of renal glomerular dysfunction, this increase on statin treatment had been feared to indicate a negative effect on renal function.

However, all current evidence is that the increase in urinary protein is from the renal tubular cells, not the glomeruli, and is due to cholesterol synthesis inhibition the tubular cells but is not associated with any decline in renal function.


Weitz & Luxenberg is no longer accepting new Crestor cases.


see also:

Tufts Study Crestor Side Effects Dangers, Tufts-New England Medical Center Study Press Release
Crestor side effects: Tufts Study: Twice as likely as similar statins.

LDL and HDL Cholesterol Crestor Cholesterol Information - LDL and HDL Cholesterol
Crestor - The Difference between LDL (bad) and HDL (good) Cholesterol

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