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What You Need to Know about the Link Between Gleevec and Heart Failure


Novartis adds congestive heart failure to Gleevec Precautions

October 3, 2006 (MedPage Today)

Novartis Oncology has announced that it is mailing information to U.S. doctors, informing them of a possible link between Gleevec (imitinib mesylate) and congestive heart failure.

Gleevec, an oral tyrosine kinase inhibitor approved by the Food and Drug Administration in 2001, is prescribed for gastrointestinal stromal tumors (GIST) and chronic myeloid leukemia.

Nature Medicine published the results of animal studies that suggested that a side effect of Gleevec may be cardiac dysfunction.


see also:

Xigris FDA statement abut Xigris: drug can cause bleeding in sepsis patients
Early communication issued by the FDA about Xigris safety review

Ziagen/Combivir Tampering Led to Misbranding of Ziagen as Combivir, counterfeit labels
HIV Meds Ziagen & Combivir Mislabeled With Counterfeit Labels

Blood Glucose Meters Abbott Notifies Users of Blood Glucose Meters to Check Display Screen
Blood glucose test results could be compromised if meter is dropped
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