Malpractice News: Gene Linked to Side Effects in Statin Drugs

Malpractice News: A study published in the August 2008 edition of the New England Journal of Medicine discusses a study regarding testing for the side-effects of statin drugs.

Statins are commonly prescribed to patients with high cholesterol problems in order to lower LDL (so called “bad” cholesterol) levels. One of the side effects of the drug is muscle pain and weakness, which affects 1 out of 10,000 patients per year.

Researchers have now identified a genetic variation that appears to predict more than half of the side effect cases. Patients in two research studies who were diagnosed with the gene variant and took statins were approximately five to 17 times more likely to develop serious muscle problems, which can ultimately lead to muscle breakdown, kidney failure and death.

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