Mesothelioma Publication - Pathogenesis

The following is an abstract of an article about the pathogenesis of mesothelioma.  The article was published at PubMed by the NIH.

Mesothelioma pathogenesis, facts and expectations.

Jaurand MC.
Inserm E 03.37, Faculte de Medecine, 8, rue du General Sarrail, Creteil 94010 cedex, France. jaurand@im3.inserm.fr
Pathol Biol (Paris). 2005 Feb;53(1):41-4.

It is the merit of Dr J.C. Wagner and his co-workers to have triggered the research on mesothelioma, going back to 1960 when they published data demonstrating a relationship between mesothelioma occurrence and exposure to asbestos fibres in the Cape Province, in South Africa.

From that time, epidemiological and toxicological investigations were performed in order to better define the occupational and environmental background of this pathology, to identify the fibre parameters accounting for the toxic effects, and to understand their mechanisms of action. Improvements in our knowledge in these areas benefited to health issues, by preventing risks associated with exposure to mineral fibres and by recognising the disease.

Due to the actual progresses in the fields of biology and biotechnologies, the research on mesothelioma presently focuses on study of the mechanisms of mesothelial cell transformation, and on development of strategies to kill tumour cells. While mesothelioma benefited to fibre toxicology and allowed to improve the management health related issue, it would be a just return if the present advances in different scientific areas will permit a rapid eradication of the disease.

Exposure to asbestos is known to cause serious illnesses such as mesothelioma, asbestos-related lung cancer or asbestosis.

If you or a loved one has been diagnosed with an asbestos illness, contact our lawyers today for a free review of your case. A Weitz & Luxenberg representative will contact you as soon as possible.