Surgeon's Treatment for Mesothelioma: Heated Intraoperative Intraperitoneal Chemotherapy
Mesothelioma surgeon Paul Sugarbaker at the Washington Cancer Institute pioneered a procedure known as heated intraoperative intraperitoneal chemotherapy.
In that procedure, used to treat mesothelioma, the surgeon removes as much of the tumor as possible. That health professional then administers chemotherapy, heated to between 40 and 48°C, in the abdomen.
The fluid is perfused for an hour to 120 minutes and then drained.
This technique permits the administration of high concentrations of selected drugs into the abdominal and pelvic surfaces. Heating the chemotherapy treatment increases the penetration of the drugs into tissues. Also, heating itself damages the malignant cells more than the normal cells.
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