Crestor Rhabdomyolysis

Users of the drug Crestor are at risk for developing Rhabdomyolysis.

Rhabdomyolysis is the breakdown of skeletal muscle due to injury.

The injury can be from physical damage to the muscle, but significant cases of rhabdomyolysis are more commonly due to high fever or hyperthermia, metabolic disorders, excessive exertion, convulsions, choreoathetosis, muscle trauma, flow of electric current through the body or anoxia of the muscle (e.g. Bywaters' syndrome, a tourniquet left for several hours, local muscle compression due to comatose states, etc.).

A large number of drugs may cause rhabdomyolysis through several mechanisms, such as myotoxicity (for example, animal toxins, antibiotics, statins, alcohol, etc), circulatory ischemia, hyperpyrexia, long duration muscle rigidity and others.

Drug-induced rhabdomyolysis is more common nowadays than in the past, due to the introduction of increasingly more potent drugs into clinical practice.

Any drug which directly or indirectly impairs the production or use of adenosine triphosphate (ATP) by skeletal muscle, or increases energy requirements so as to exceed ATP production, can cause rhabdomyolysis (Larbi, 1998).

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see also:

LDL and HDL Cholesterol Crestor Cholesterol Information - LDL and HDL Cholesterol
Crestor - The Difference between LDL (bad) and HDL (good) Cholesterol

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Crestor Risk: Rhabdomyolysis - the breakdown of skeletal muscle

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