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Quetiapine

in this section: Quetiapine Fumarate | Quetiapine


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Seroquel Quetiapine

Seroquel, in more technical terms, is also known as Quetiapine.

Quetiapine has an antagonistic effect on the histamine receptor. This may be responsible for the sedative effect of the drug.

The antipsychotic effect of quetiapine is thought to be mediated through antagonist activity at dopamine and serotonin receptors. Specifically the D1, D2, 5-HT1A and 5-HT2 receptor subtypes are antagonized.

Theoretically, this allows for normal physiological surges of dopamine to elicit their normal effects in areas such as the nigrostriatal and tuberoinfundibular pathways, thus minimizing the risk of side effects such as pseudo-parkinsonism and elevations in prolactin.

Serial PET scans evaluating the D2 receptor occupancy of quetiapine have demonstrated that quetiapine very rapidly disassociates from the D2 receptor.

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see also:

Quetiapine Fumarate Seroquel Quetiapine Fumarate
Seroquel Quetiapine Fumarate is used to treat many disorders.

Seroquel The Drug Seroquel Drug- Atypical Antipsychotic Drug (quetiapine fumarate)
Seroquel Drug- an Antipsychotic drug that treats many disorders

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