Strattera & Jaundice - Strattera increases Jaundice risk

Stattera danger: Jaundice

Jaundice is a side effect from the ADHD drug Strattera.

Jaundice is a yellowing of the skin, sclera (the white of the eyes) and mucous membranes caused by increased levels of bilirubin in the human body. Usually the concentration of bilirubin in the blood must exceed 2–3mg/dL for the coloration to be easily visible.

When red blood cells die, the heme in their hemoglobin is converted to bilirubin in the spleen and in the Kupffer cells in the liver. The bilirubin is processed by the liver, enters bile and is eventually excreted through feces.

Consequently, there are three different classes of causes for jaundice. Pre-hepatic or hemolytic causes, where too many red blood cells are broken down, hepatic causes where the processing of bilirubin in the liver does not function correctly, and post-hepatic or extrahepatic causes, where the removal of bile is disturbed.

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