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Onglyza and Kombiglyze XR are approved for use with diet and exercise to control blood sugar in adults with type 2 diabetes.

Results from a saxagliptin clinical trial found a significantly increased risk of hospitalization due to heart failure in saxagliptin-treated patients, and a subsequent safety review conducted by the U.S. Food and Drug Administration (FDA) found that saxagliptin, contained in the medications Onglyza and Kombiglyze XR, may increase the risk of heart failure, particularly in those who already have heart failure or impaired kidney function.

Signs/Symptoms of Heart Failure

Heart failure can occur when the heart cannot pump enough blood to meet the body’s needs. As the FDA notes in its Safety Communication, signs and symptoms of heart failure may include:

  • Unusual shortness of breath during daily activities
  • Trouble breathing when lying down
  • Tiredness, weakness, or fatigue
  • Weight gain with swelling in the ankles, feet, legs, or stomach

Victims of Heart Failure Occurring with Onglyza or Kombiglyze XR Use May Be Entitled to Compensation

If you or a loved one took Onglyza or Kombiglyze XR before April 5, 2016, and were diagnosed with heart failure (sometimes called “congestive heart failure”, “CHF” or “cardiac failure”) or required hospitalization due to heart failure, you may be entitled to compensation.

If you are the loved one of someone who took Onglyza or Kombiglyze XR and died as a result of heart failure while on these medications, please contact us. You may be able to receive compensation for your loved one’s death.

We May Be Able to Help

We have been helping clients win cases for more than 25 years. As a leading personal injury law firm recognized across the country, we have committed ourselves to holding irresponsible parties accountable, and we have won more than $17 billion for our clients.

We would feel privileged to offer you our assistance. For more information about your legal options and a free consultation, please contact us at  or complete our online form. One of our client relations representatives will be in touch with you shortly.